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Telomerase gene therapy

Telomerase gene therapy seems to have extended mice lifetimes and improved health and age related diseases. They applied the therapy to adult mice, not embryos, and they used a DNA modified virus to deliver the therapy. The first linked article mentions an average life extension of 24%. The original article (EMBO Molecular Medicine) is here.
posted by aleph on Dec 9, 2012 - 40 comments

'Resetting' the biological clock

First Gene Therapy Successful Against Aging-Associated Decline: Mouse Lifespan Extended Up to 24% With a Single Treatment A new study consisting of inducing cells to express telomerase, the enzyme which -- metaphorically -- slows down the biological clock -- was successful. The research provides a "proof-of-principle" that this "feasible and safe" approach can effectively "improve health span." [article]
posted by T.D. Strange on May 15, 2012 - 97 comments

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