We're putting human brain bits in mice and they're growing in there
November 13, 2017 10:45 AM Subscribe
"These micro quasi-brains are revolutionizing research on human brain development and diseases from Alzheimer’s to Zika, but the headlong rush to grow the most realistic, most highly developed brain organoids has thrown researchers into uncharted ethical waters....In the previously unreported experiments implanting human brain organoids into lab rodents, most of the transplants survived....More notably, the human organoids implanted into mice connected to the rodent’s circulatory system, making this the first reported vascularization. And mature neurons from the human brain organoid sent axons, the wires that carry electrical signals from one neuron to another, into “multiple regions of the host mouse brain,” according to a team led by Fred “Rusty” Gage of the Salk Institute".
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