Gotta die sometime and from something.
April 25, 2011 3:51 PM Subscribe
What Is Good for the Heart May Not Be Good for the Prostate, Study Suggests.
posted by VikingSword (120 comments total)
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In a major study that appears to overturn a lot of previous research
, the largest and most authoritative study ever to examine the association of dietary fats and prostate cancer risk has found an inverse association in the effect of Omega-3 fatty acids in heart disease and in prostate cancer. A lot of recent conventional wisdom has been upended, with the role of all fatty acids undergoing substantial revisions in our understanding.
'Analyzing data from a nationwide study involving more than 3,400 men, researchers at Fred Hutchinson Cancer Research Center found that men with the highest blood percentages of docosahexaenoic acid, or DHA, an inflammation-lowering omega-3 fatty acid commonly found in fatty fish, have two-and-a-half-times the risk of developing aggressive, high-grade prostate cancer compared to men with the lowest DHA levels.'
'Conversely, the study also found that men with the highest blood ratios of trans-fatty acids -- which are linked to inflammation and heart disease and abundant in processed foods that contain partially hydrogenated vegetable oils -- had a 50 percent reduction in the risk of high-grade prostate cancer. In addition, neither of these fats was associated with the risk of low-grade prostate cancer risk. The researchers also found that omega-6 fatty acids, which are found in most vegetable oils and are linked to inflammation and heart disease, were not associated with prostate cancer risk. They also found that none of the fats were associated with the risk of low-grade prostate cancer.'
'"We were stunned to see these results and we spent a lot of time making sure the analyses were correct," said Brasky, a postdoctoral research fellow in the Hutchinson Center's Cancer Prevention Program. "Our findings turn what we know -- or rather what we think we know -- about diet, inflammation and the development of prostate cancer on its head and shine a light on the complexity of studying the association between nutrition and the risk of various chronic diseases."'
But the role of fatty acids in heart disease has already been questioned by recent studies even in heart disease. For example, a lot of the claimed benefits of omega-3 fatty acids in heart disease was speculated to be down to lowering the frequency of atrial fibrillation. Now it seems that is false, as the use of omega-3 does not appear to reduce recurrence of atrial fibrillation
Worse, major studies into n–3 fatty acids and cardiovascular events
have been questioned.