I read that as not-heterosexual (aka gay/lesbian/bi), but still cis-gendered (identifying as the gender closest to your biological sex).
syntaxfree, you're missing a pretty significant item on your list: how crappy your friend is feeling now, and how well they could handle trying to deal with gender dysphoria for the rest of their life. I'd encourage you simply to support your friend and refrain from trying to convince them to follow a particular path that you calculate to be optimal.
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