"published online today inScience Translational Medicine, he and colleagues report the development of microparticles filled with oxygen gas that can be injected directly into the bloodstream. The particles quickly dissolve, releasing the gas and keeping organs, such as the brain, from suffocating. [...]
The microparticles are tiny bubbles whose surfaces are membranes already used clinically to administer chemotherapy drugs and ultrasound dyes. But while those microparticles release their contents slowly, Kheir and his collaborators designed oxygen-containing particles that would dissolve as soon as they hit the bloodstream. They then tested the microparticles in rabbits breathing air low in oxygen. Within seconds of receiving the microbubbles, the levels of oxygen in the rabbits' blood rose from a dangerously low 70% to nearly 100% saturation, the ideal level.
"Essentially as soon as we started injecting it, clinically we started to see an effect," says Kheir. But if the injection stopped, the levels fell just as quickly, he says, indicating the need for the microparticles to be continuously administered.
... large animal trials that are currently underway...
For now, the microparticles are bathed in so much fluid that—especially in young or small patients—the volume is a limiting factor in how long people could receive the infusion. The current maximum is around 15 to 30 minutes, Kheir says. "If we could increase the ratio of microparticles to fluid, we might be able to use this for even longer, and even more indications.""
Lance Armstrong said in his bio he had an edge because he was able to get more oxygen into his blood than normal people due to his genetic makeup (something about his lungs).
And what we consider natural causes has changed as medicine has progressed, you know.
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