I am pretty sure the increased range of certain ticks that carry, say Lymes, is directly attributable to climate change.
The rOspA vaccine seems to have a unique mode of action. [...] Data from animal models suggest that protective OspA antibodies from the immunized host destroy B burgdorferi in the midgut of the tick, preventing transmission to the host. The vaccine-induced protection thus occurs primarily before the B burgdorferi enters the host.
Are there human versions of that dog medicine that kills them in 12 hours? If not, why not?
Tick paralysis results from inoculation of a toxin from tick salivary glands during a blood meal. The toxin causes symptoms within 2–7 days, beginning with weakness in both legs that progresses to paralysis. The paralysis ascends to the trunk, arms, and head within hours and may lead to respiratory failure and death. The disease can present as acute ataxia without muscle weakness.
Patients may report minor sensory symptoms, but constitutional signs are usually absent. Deep tendon reflexes are usually hypoactive or absent, and ophthalmoplegia and bulbar palsy can occur.
Tick paralysis occurs when an engorged and gravid (egg-laden) female tick produces a neurotoxin in its salivary glands and transmits it to its host during feeding. Experiments have indicated that the greatest amount of toxin is produced between the fifth and seventh day of attachment (often initiating or increasing the severity of symptoms), although the timing may vary depending on the species of tick.
Making Sense of Testing [PDF]
Why scans and health tests for well people aren't always a good idea.
Adverts and media reports say that people with no symptoms, nor reason to suspect they have a disease can find out what they will get in the future, “reverse the disease processes before symptoms appear”, or even discover how they will die. People are promised instant results, valuable insights and ‘peace of mind’. What many people are getting is a lot of confusion and anxiety, ongoing trips to the doctor and, sometimes, unnecessary medical procedures. The guide presents a few insights and highlights common misconceptions about having health tests and scans.
Making Sense of Screening [PDF]
A guide to weighing up the benefits and harms of health screening programmes
Public expectations about screening don't match what screening programmes can deliver. By addressing misconceptions about how screening works, its limitations and the calculation of benefits and harms, scientists and clinicians hope to bridge the gap between the active debates of the scientific community and the concerns raised by the public.
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