It is possible that if the damage were restricted solely to the axons and you waited long enough, they would just regrow back to their old targets. This appears to be what happened here.on what actually happened in his brain.
What is extraordinary about this case is that such widespread rewiring is nearly unheard of. The classical belief is that in the central nervous system (CNS) -- as opposed to the peripheral nervous system (PNS) -- regrowth of axons is suppressed by a signaling pathway that is at least partially known (involving proteins like Nogo and Nogo-R). Under this system regrowth of this nature should not occur. Even more than that, it is remarkable that after the axons started growing they managed to find their original targets. The process of axon pathfinding is complicated and involves many signalling molecules that direct the axons to the right place. It is not what I would have expected that those signals would still be present in the brain of an adult.
We know that neurons in your brain very rarely divide, but under some circumstances axons can regrow -- provide the neuron cell body is intact. It is possible that if the damage were restricted solely to the axons and you waited long enough, they would just regrow back to their old targets. This appears to be what happened here.What were the "entirely new structures not found in normal brains?" I don't see that in the link.
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But how wicked cool for Terry Wallis to have "recovered" and reawoken!
posted by fenriq at 6:59 PM on July 4, 2006 [1 favorite has favorites]