Schizophrenia, Bipolar, Autism, Depression disorders share genes
February 9, 2018 12:01 PM Subscribe
Second breakthrough in two years for humankind's commonest mental illnesses. Published in Science today, Gandal et al. show correlations in gene expression between Schizophrenia and three other major mental illnesses: 70% for Bipolar disorder, 45% for Autism spectrum disorder and 30% for Major Depressive disorder. This research comes exactly two years after Sekar et al. published an in-depth discovery that a known gene from the immune system was over expressed in the brains of Schizophrenics. 'Complement Component C4' gene flags connections between neurons for destruction in a late-adolescent process that called "synaptic pruning" and which is devastatingly overactive in Schizophrenia (previously). In the years ahead will these two findings merge into a scientific picture that our brains are profoundly shaped by our immune systems in late childhood?