a rather experimental, yet remarkably effective treatment whereby feces from a healthy donor are placed within a C. diff patient’s intestines, either through an enema, colonoscope, or tube inserted through the nose.
Humans have taste receptor cells in the gut, the voice box, the upper esophagus, but only the tongue's receptor's report to the brain. "Which is something to be thankful for," says Danielle Reed ... . Otherwise you'd be tasting things like bile and pancreatic enzymes. (Intestinal taste receptors are thought to trigger hormonal responses to molecules, such as salt and sugar, and defensive reactions - vomiting, diarrhea - to dangerous bitter items.)
A paper published Wednesday evening in the New England Journal of Medicine may give those patients assistance, and change those doctors’ minds. It represents the first report from a completed randomized trial of fecal transplants, and it finds that the treatment worked much better than the powerful antibiotics that are usually given for C. diff infection — so much better, in fact, that the trial was ended early, because the monitoring board supervising the trial’s execution could not ethically justify withholding the transplants from more patients.
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