NARF!
May 28, 2009 10:40 AM
Subscribe
We will speak to the Mouse.FoxP2, a forkhead box transcription factor has long been thought to be the "language gene", as all animals that have it can communicate verbally. Without it,
songbirds don't learn their songs,
humans can't speak properly and
mice can't make their sweet ultrasonic sounds. Human Foxp2 has been claimed to be a site of recent, strong selection in the human genome, with several alterations in sequence from our most closely related ancestors. So the question: Is the human version of FoxP2 itself a determinant for our ability to speak in ways our chimp cousins cannot?
Svante Paabo, who you may know from the Neanderthal genome work, has just published a
study of Foxp2 humanized mice. Alas, the gene does not seem to function correctly, in the mousely brain context, and the ultrasonic vocalizations of the humanized mice are impaired. Apparently a single gene is not enough to humanize.
But what if it worked? what sort of world would we be living in if the reverse Doolittle were possible?
Previously on Metafilter
posted by Cold Lurkey (56 comments total)
7 users marked this as a favorite
posted by dunkadunc at 10:43 AM on May 28, 2009