You may be wondering if eating brains is entirely safe. Besides being high in cholesterol, the brain is the main area where prions known to cause transmissible spongiform encephalopathy congregate in the body. In cows it's called Mad Cow disease (Bovine Spongiform Encephalopathy), Scrapie in sheep, and Chronic Wasting Disease in deer and other wild game. Creutzfeldt-Jakob disease and Kuru are two forms of spongiform encephalopathy in humans. Kuru was intensely studied among the Fore tribe of Papua New Guinea from the 1950's to the 70's and it was determined that the high instances of it in the tribe were due to their ritual endocannibalistic funeral practices. It has been posited recently that a resistance to prionic diseases may have been selected for in our ancestors, suggesting that cannibalism was not uncommon.